Journal Ultrasound is now indexed on PubMed Central
S Acar, E Millar, M Mitkova and V Mitkov, Diagnostic Imaging Department, Milton Keynes University Hospital, UK and Ultrasound Diagnostics Department, Russian Medical Academy of Postgraduate Education, Moscow, Russia
The aim of the study was to assess the accuracy of ultrasound shear wave elastography in the diagnosis of adenomyosis. 153 patients were examined. 97 patients were with suspected adenomyosis and 56 patients were with unremarkable myometrium. Adenomyosis was confirmed in 39 cases (A subgroup) and excluded in 14 cases (B subgroup) in the main group based on morphological examination. All patients underwent ultrasound examination using an Aixplorer (Supersonic Imagine, France) scanner with application of shear wave elastography during transvaginal scanning. Retrospective analysis of the elastography criteria against the findings from morphological/histological examination was performed.
The following values of Young’s modulus were found in subgroup A (adenomyosis): Emean – 72.7 (22.6–274.2) kPa (median, 5–95th percentiles), Emax – 94.8 (29.3–300.0) kPa, SD – 9.9 (2.6–26.3) kPa; in subgroup B (non adenomyosis) –28.3 (12.7–59.5) kPa, 33.6 (16.0–80.8) kPa, 3.0 (1.4–15.6) kPa; in control group – 24.4 (17.9–32.4) kPa, 29.8 (21.6–40.8) kPa, 2.3 (1.3–6.1) kPa, respectively (P < 0.05 for all comparison with subgroup В and control group). The Emean cut-off value for adenomyosis diagnosis was 34.6 kPa. The sensitivity, specificity, positive predictive value, negative predictive value, and area under curve (AUC) were 89.7%, 92.9%, 97.2%, 76.5%, and 0.908. The Emax cut-off value was 45.4 kPa (89.7%, 92.9%, 97.2%, 76.5%, and 0.907 respectively).
This study showed a significant increase of the myometrial stiffness estimated with shear wave elastography use in patients with adenomyosis.
The full article is available in the November 2016 issue of Journal Ultrasound.
ECHOES by Hazel Edwards
The utility of ultrasound elastography in differentiation of endometriomas and hemorrhagic ovarian cysts. Batur A, Yavuz A, Ozgokce M, et al. J Med Ultrason 2016; 43: 395-400.
This study aimed to differentiate between endometriomas and haemorrhagic cysts by using shear wave elastography. The researchers evaluated 78 ovarian cysts in 70 women and achieved a sensitivity and specificity of 82.1% and 79.2% respectively. Endometriomas are much stiffer than haemorrhagic cysts. The clinical value is that unnecessary surgery may be avoided.
More Echoes are available in the November 2016 issue of Journal Ultrasound.